Neue Möglichkeiten für die Strukturbestimmungvon Membranproteinen

Theresa Gewering, Arne Möller
Membrane proteins establish the connection between the outside and
the inside of a cell. Even though 30 % of proteins in a cell are membrane
associated, their structural data is strongly underrepresented due to
the high flexibility and low purification yield. The resolution revolution
in cryo-EM opened up new opportunities to solve structures of dynamic
membrane proteins that can only be purified in small quantities.