Frozen motion: how cryo-EM changes the way we look at ABC transporters

Dmitry Shvarev, Dovile Januliene, Arne Moeller ATP-binding cassette (ABC) transporters are widely present molecular machines that transfer substrates across the cell membrane. ABC transporters are involved in numerous physiological processes and are often clinical targets. Structural biology is fundamental to obtain the molecular details underlying ABC transporter function and suggest approaches to modulate it. Until …

Frozen motion: how cryo-EM changes the way we look at ABC transporters Read More »